Promethazine is contraindicated in comatose states, As well as in folks acknowledged to generally be hypersensitive or to have experienced an idiosyncratic response to promethazine or to other

Even though it helps Lots of individuals, this medication incorporates a possibility for abuse and could occasionally result in dependancy. This risk might be higher Should you have a compound use dysfunction (for example overuse of or habit to drugs/Alcoholic beverages).

Read the Medication Manual if out there out of your pharmacist Before you begin taking this solution and every time you receive a refill. In case you have any questions, ask your health care provider or pharmacist.

The cough syrup codeine linctus will now only be available to individuals with a prescription resulting from fears more than abuse and dependancy.

Because of comparable pharmacologic Homes, it is actually fair to expect comparable hazard with concomitant usage of opioid cough drugs and benzodiazepines, other CNS depressants, or alcohol.

Suitable for Older people and kids aged 16 and above, Night Nurse is available in handy capsules or liquid structure.

g., amiodarone, quinidine) may check here perhaps bring about a rise in codeine plasma concentrations and a decrease in Lively metabolite morphine plasma focus which could cause an analgesic efficacy reduction or signs or symptoms of here opioid withdrawal.

In the event the response to an opioid antagonist is suboptimal or only transient in website mother nature, administer further antagonist as directed because of the products’s prescribing facts. The respiratory Hi-Tech promethazine syrup depressant outcomes of promethazine are usually not reversed by opioid antagonists, for example naloxone.

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals lower than six decades of age, because The mixture could cause lethal respiratory depression During this age population (see WARNINGS Box Warning and Use in Pediatric People).

Sedating medicines might lead to confusion and above-sedation from the elderly; elderly people typically must be started on lower doses of Promethazine Hydrochloride and Codeine Phosphate Syrup and noticed closely.

As a result of probable for promethazine to reverse epinephrine’s vasopressor result, epinephrine should NOT be used to deal with hypotension affiliated with promethazine overdose.

To reduce the risk of dizziness and lightheadedness, rise read more up slowly but surely when increasing from a sitting down or lying situation.

Responses for the session recognized the tension pharmacists have been under to offer the drugs to People struggling from habit.

Codeine is thought being significantly excreted by the kidney, and the risk of adverse reactions to this drug could possibly be larger in people with impaired renal functionality.